Abstract
Pseudomonas aeruginosa is a zoonotic pathogen. Commercial poultry are susceptible to P aeruginosa infections, especially at young ages, with high mortality. P. aeruginosa employed beta-lactamases, efflux pumps, and alterations at the target site or in the outer membrane as resistance mechanisms. Resistance to multiple antibiotics is typically caused by activation of a single, powerful resistance mechanism or by the fusion of multiple distinct mechanisms within a single isolate. Results in the MIC revealed that the REO at 100% and 75% concentrations were highly significant compared with the positive control. Meanwhile, FICI for the three treatments, 75%, 50%, and 25%, showed indifferent interactions between virgin coconut oil and the REO. Data gathered during the sensitivity analysis showed that the REO against P. aeruginosa after 24 hours of post exposure, 70% to 100% concentrations were highly significant in inhibiting the growth. . .
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